The Fascist regime poured in large investments, for instance with the setting up of a large tobacco manufacturing plant in 1937. Subsequently, the city started to increase quickly and became one of many primary industrial commerce centres of northern Italy because of a system of canals that allowed barges and ships to come and go. Believed to have been established in 1088, the University of Bologna is widely thought-about the world’s oldest college in steady operation. The college originated as a centre for the examine of medieval Roman regulation beneath major glossators, including Irnerius. It numbered Dante, Boccaccio and Petrarch among its students. By 1200, Bologna was a thriving commercial and artisanal centre of about 10,000 individuals.